Toward SERS-based dynamic detection of insulin diffusing through hydrogel matrices

Transplantation of the immunoprotected pancreatic islets in microspheres made of non-covalently crosslinked hydrogels is promising therapy in the type 1 diabetes mellitus. The work investigates the possibility of monitoring the diffusion process of insulin molecules through alginate-based hydrogel matrices

Keywords: Insulin, alginate-based hydrogel matrices, Surface Enhanced Raman Scattering